Insomnia or other sleep disturbances

Insomnia means difficulty in falling asleep and/or stays asleep. Insomnia commonly leads to daytime sleepiness, lethargy, and a general feeling of being unwell. The most common treatment of insomnia includes GABAA receptor positive allosteric modulators or Melatonin agonists.

Magnesium, a cofactor involved in more than 300 enzyme systems, regulates diverse biochemical reactions in the body.

Recently, magnesium has also been found to regulate cellular timekeeping in both animal and plant cells, thus it is beneficial to maintain the normal circadian rhythms and ensure a quality sleep in humans.

Magnesium supplement use improves insomnia symptom among older people in a double-blind placebo-controlled clinical trial.

Low dietary magnesium intake was found to be significantly associated with depression. It is known that depression is associated with poor sleep. However, the studies on dietary magnesium and sleep are limited.